| RU486
We began offering medical abortion with RU-486 in January
2001. With our protocol over 95% of women complete the abortion
by the afternoon of the second day.
If you live more than an hour drive outside Little Rock you
must agree to stay in Little Rock (usually at a motel) for
at least one night. You must also be 56 days (8 weeks) or
less from your last period by ultrasound. You will be required
to have at least 2 visits. Your first visit will be for ultrasound,
counseling and taking the RU-486 (mifepristone). The second
visit will be the following morning so that we can determine
with the ultrasound that the uterus is empty.
The cost of a medical abortion is listed in the fees schedule.
The fee covers RhoGam if needed and all medications except
for narcotic pain medication which must be obtained at a pharmacy.
The charge will cover the costs of a surgical abortion in
our clinic if the drug fails to cause a complete abortion.
Additionally the fee covers a follow up visit in 4 weeks.
The fee does not cover medical care obtained outside our clinic.
A surgical abortion is necessary in about 5% of cases (1 in
20 women have to have a surgical abortion).
| Fast
Facts About Mifepristone (RU486) |
| What
is Mifepristone? |
| Mifepristone (formerly
known as RU486) is a medication that blocks the action
of the hormone progesterone. Progesterone is needed to
sustain a pregnancy. Mifepristone has been used, in combination
with other medications called prostaglandins, for medical
abortion since 1988 in France and China, and since the
early 1990's in the United Kingdom and Sweden. It has
been more recently licensed in nine other European countries
and Israel. Millions of women worldwide have safely used
mifepristone regimens to end their pregnancies. |
| How Mifepristone
works to end pregnancy |
Mifepristone blocks the
action of progesterone, which is needed to sustain a pregnancy.
This results in: • Changes in the uterine lining
and detachment of the pregnancy • Softening
and opening of the cervix • Increased uterine
sensitivity to prostaglandin
Mifepristone is used in combination with another medication,
a prostaglandin called Misoprostol (Cytotec). Misoprostol
causes the uterus to contract, and helps the pregnancy
tissue to pass. |
| How effective
is the combination of Mifepristone and Misoprostol in
terminating an early pregnancy? |
| Approximately
95% of women will have a complete abortion when using
Mifepristone/Misoprostol up to 56 days after the first
day of the last menstrual period. The remaining women
will need a suction abortion. |
| Treatment
regimen with Mifepristone/Misoprostol |
| Please
note: After FDA approval of Mifepristone/Misoprostol
there has been new clinical data about the effectiveness
of various regimes that vary from the one that the FDA
approved. We are using one of these regimes which has
been shown to be safe, effective and is more convenient
for women using the method. |
| Step
One, at the clinic |
• A medical history
is taken, an ultrasound is done and a clinical exam and
lab tests are performed.
• Counseling is completed and informed consent is
obtained.
• If eligible for medical abortion, then you will
swallow the Mifepristone pills. |
| Step Two,
at home (or motel) |
| • Six to 8 hours
after the Mifepristone pill has been swallowed you will
place 4 Cytotec tablets deep inside your vagina. This
will take place at your home or hotel room. |
| Step Three,
return to the clinic the following morning |
| •
You will return at 9 AM the following morning to have
an ultrasound to see if the abortion is complete. You
should not have anything to eat or drink after midnight
other than sips of water to take the pain medication.
If the abortion is complete you will be discharged home
and asked to take a urine pregnancy test in 3 weeks.
You are also encouraged to return to the clinic in 4
weeks to have a follow up examination that is done at
no additional charge.
• If you have not had a complete abortion you
will be given 4 Cytotec to place in your vagina, at
this time you may return to your motel room or remain
in the clinic. You may eat a light breakfast and drink
clear liquids in the first hour after you leave the
clinic. You should then have nothing by mouth until
after you return to the clinic in the afternoon.
• You must return to the clinic by 2 PM at which
time another ultrasound will be done. If you have not
passed the pregnancy, you must have
a surgical abortion at that time.
• From past studies it is anticipated that over
95% of women will have a successful medical abortion,
the remainder will require a surgical abortion. The
surgical abortion is done in our clinic at no additional
cost. You can have IV sedation with the surgical abortion
if you have someone to drive you home.
• After leaving the clinic you should have a pregnancy
test in 3 weeks. You are also encouraged to return to
the clinic in 4 weeks to have a follow up examination
that is done at no additional charge. You should call
us anytime you are having complications such as severe
pain, heavy vaginal bleeding, a fever or other signs
of an infection. |
| Possible
side effects of a mifepristone abortion |
| Side
effects, such as pain, cramping and vaginal bleeding,
result from the abortion process itself, and are therefore
expected with a medical abortion.
Other side effects of the medications themselves may
include nausea, vomiting, diarrhea, chills, or fever.
Complications are rare, but may include excessive vaginal
bleeding requiring transfusion (occurs in approximately
1 in 1000 cases), incomplete abortion which requires
a suction abortion (see above).
There have been several reports of death in the United
States and Canada associated with medical abortion due
to a bacterial infection. Since there have been many
millions of women who have used Mifepristone without
complications, this is a very rare complication. Since
this type infection has not been reported with surgical
abortion, surgical abortion carries less risk of death
than medical abortion. |
| What
women can expect from a Mifepristone abortion |
• Medical abortion
with Mifepristone/Misoprostol requires at least two visits
to the clinic.
• Approximately 95% of women using Mifepristone/Misoprostol
up to 56 days since the last menstrual period will have
a complete medical abortion. • Approximately two-thirds of
women will have a complete medical abortion within 4 hours
of using the misoprostol. • Approximately
90% of women will have a complete medical abortion within
24 hours of using the misoprostol. •
On average, women may expect to have bleeding and/or spotting
for 9-16 days. • Women may pass clots,
ranging in size. • Some women may see
grayish pregnancy tissue. • If the medications
fail to end the pregnancy, a suction abortion must be
performed. At this clinic, a woman who chooses medical
abortion must be willing to have a suction abortion the
following afternoon if the medical abortion is not complete.
|
| Reasons
you may not qualify to have a medical abortion |
It has been more than
56 days (eight weeks) since your last menstrual period
began as determined by ultrasound.
• If you have an IUD, it must be taken out before
you use mifepristone.
• You have problems with your adrenal glands (chronic
adrenal failure) or severe heart, liver, or kidney problems.
• You take a medication to thin your blood.
• You have a certain bleeding problems.
• You take certain steroid medications.
• You cannot return for the follow-up visit(s).
• You cannot easily get emergency medical help should
a problem occur.
• You are allergic to Mifepristone, Misoprostol,
or medicines that contain misoprostol (Cytotec).
• You are not sure that you want to end your pregnancy
and you would be unwilling to have a surgical abortion
if the medication abortion fails. |
|